Circadian physiology with Prof Karyn Esser
This week on the podcast I speak to physiologist Professor Karyn Esser all about circadian biology and the importance of it for health.
Prof Esser talks about what we know with regards to what impacts the circadian rhythm (and what even is it?) and how important regulating both our master clock and the peripheral clocks for our overall health outcomes. We discuss how exercise impacts our circadian biology, and if there is a ‘better’ time of day to do exercise. We also talk about the impact of the circadian rhythm on metabolising different nutrients and what we do or don’t know about the impact of the circadian rhythm on the absorption of pharmaceuticals and supplements. We also talk about sex differences. This is a great conversation and I think you’re going to love it.
Dr Esser is a Professor of Physiology and Associate Director of the Myology Institute at the University of Florida.
Her lab has been working in the area of skeletal muscle adaptation for over 20 years. Initially research was focused on understanding the molecular mechanisms that underlie adult skeletal muscle adaptation to exercise. However, in 2002 they were using an early generation microarray assay and discovered that genes important for circadian rhythms were also at work in skeletal muscle. Since that early observation, her lab has pioneered research on the role of circadian rhythms and the circadian clock mechanism in skeletal muscle.
Currently our lab is focused on; 1) basic science experiments to define the genomic network downstream of the clock that modulates muscle health. 2) learning how age changes the clock function in skeletal muscle and other tissues; and 3) learning how exercise works with the circadian clock to help promote tissue and systemic health
Dr Karyn Esser can be found here https://www.linkedin.com/in/karyn-esser-a187333